Still, not a bad summary, regardless. Got most of the major games in there.
Source: http://www.joystiq.com/2011/12/29/gaming-in-2011-a-two-minute-video-roundup/
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A new report suggests just how far public schools have to go to reach the state's goal of improving student performance, high school graduation rates and eventual success in college.
For the 35,671 high school students who graduated from Connecticut public high schools in 2004, just two in five had earned a degree or certificate from college six years later.
Another one-third started college during this time but did not finish. One-quarter skipped post-secondary education altogether.
Locally, the percentage of students successfully completing a college program six years out of high school ranged from 6 percent at Henry Abbott Technical High School in Danbury to 73 percent at Ridgefield High School.
Suburban high school graduates find more success at college than urban students, the report shows.
The data came from the National Student Clearinghouse, a central repository of enrollment and graduation data, and was requested by the state's Board of Regents for Higher Education, the state Department of Education, and P-20 Council, a collaboration between the state's early childhood, K-12, higher education and workforce training sectors.
The council, which held a series of college readiness workshops across the state this fall, is releasing the data to give policy makers and educators a better idea of what high school graduates in the state do with their diplomas.
The report provides degree completion rates by high schools in the state, information which has previously not been available in Connecticut.
Michael Meotti, vice president of the state's Board of Regents, said the report signals a need to identify ways to help students prepare to enter the workforce.
"We need to ensure that we're preparing our students for success from the very moment they set foot in our schools," Meotti said in a prepared statement. "That means identifying ways in which we can help them learn and be better able to adapt to the 21st century workforce."
The report calls for a focus on students who enter college but fail to graduate within six years.
Of the 41 percent of the class of 2004 who completed at least one degree or certificate program, half -- representing 20 percent of the class -- went to Connecticut colleges and universities, and half attended colleges or universities out of state.
In Connecticut, according to the U.S. Census, 46 percent of 25- to 34-year-olds have an associate's degree or higher. That puts the state seventh in the nation. The state's level of education attainment is slipping.
Braden Hosch, director of police and research for the Board of Regents, said the results are about what was expected.
The data also show the college-going rate between 2004 and 2009 has increased. According to the state Department of Education, 77.8 percent of the class of 2004 indicated they planned to attend college.
In actuality, 57.4 attended college, according to clearinghouse statistics that officials say are accurate within 5 percent.
In 2009, 80.5 percent said they were college-bound. The clearinghouse reports 66.9 percent enrolled the following fall.
"What we are trying to focus attention on is: What matters for Connecticut's economic competitiveness is not simply that students go to college, but when they go, they finish," Hosch said.
"We know that in the economy we have today, having some sort of credential after high school makes you much more competitive in the job market."
The report doesn't get into the reasons students don't finish. While some point to the cost of college as why some students start but don't finish college, many say not enough students enter college prepared to do the work or have the motivation to stick with it.
State Education Commissioner Stefan Pryor said there is a need for better preparation. The higher education report comes out the same day the Department of Education released a report that shows graduation rates from public high schools in 2010 showed only a slight improvement.
Nearly one in five students still fail to graduate within four years. For minority students, one in three fail to graduate with the class they entered with as freshmen.
Ten districts in the state, including Monroe, had greater than a 95 percent graduation rate in 2010. Six districts, including Bridgeport, had rates lower than 65 percent.
Contact Linda Lambeck at 203-330-6218 or lclambeck@ctpost.com. Follow her at twitter.com/lclambeck.
Source: http://www.ctpost.com/news/article/Only-2-in-5-state-high-school-grads-finish-college-2431648.php
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Source: http://dealnews.com/features/morning-jolt.html?iref=rss-dealnews-todays-edition
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While simple hooks are great for hanging your keys by the door, they can't hang everything. With a few old Lego bricks, though, you can stick nearly anything?cables, keys, pens, or anything else?to a hard surface.
The folks that make Sugru, the moldable silicone perfect for DIY projects and repairs, came up with this clever trick. Its only real downside is that you'll have a Lego brick stuck on whatever it is you're hanging, but as long as you can wrangle up some of the thinner or smaller ones, you probably won't notice much?and it works with literally anything you could want quick access to. Check out the video above for some clever examples.
Sugru ? LEGO [Warning, May Cause Excitement] | YouTube via Reddit
NASHUA, N.H. -- Ron Paul was in the Granite State campaigning for the Republican presidential nomination that he failed to capture four years ago, when he was perceived as a fringe candidate. With the lurch of the GOP to the extreme right, Paul no longer inhabits the lonely outland of conservatism as that real estate has been annexed by most Republican candidates.
However, he sharply differs with his Republican brethren (and Bachmann) on the issues of national defense and terrorism. He remains a strong, committed libertarian. At a Nashua town meeting held on Saturday, Dec. 3, he denounced the wars in Afghanistan & Iraq and the excursion in Libya. He also criticized the National Defense Authorization Act for broadening the battlefield in the War on Terror to the United States itself.
Unique
His appearance before 200 of the Ron Paul faithful revealed that his fervor to defend liberty has not diminished since he first ran for president back in 1988 as the standard bearer of the Libertarian Party. He hit on his favorite subjects such as re-implementing the gold standard and auditing the Federal Reserve System.
Ron Paul is unique among politicians in his "Damn the torpedoes! Full speed ahead!"/"My platform right or wrong" attitude. There hasn't been anyone like him since Barry Goldwater stormed the citadel of the Republican establishment and defeated the New York plutocrat Nelson Rockefeller in 1964. Ron Paul is the opposite of the proverbial "Pander Bear", the moniker Paul Tsongas hung on Bill Clinton during the 1992 New Hampshire primary.
You cannot help but respect the man. He is a puckish figure, in his cheap suit and black Reeboks, his legs crossed at the ankles as he recounted his life and beliefs to an interlocutor. He struck me as a combination of Frank Capra character and "Give 'em Hell Harry!" Truman.
Preaching to the Faithful
When the moderator of Ron Paul's town meeting asked if there were undecideds in the room, I and a handful of others raised our paws. The room was overwhelmingly populated by Ron Paul enthusiasts, and though the moderator promised that we undecideds would be called on in the question & answer period, that ukase was forgotten when that part of the meeting arrived.
It didn't matter. We all knew the man's policy positions and philosophy.
Four years ago, I did not see him in New Hampshire, but experienced some of his supporters behaving like goons, heckling John McCain at an appearance in Manchester. It gave me a bad impression, but the attendees at the event were polite, well-behaved, typically middle-class Granite Staters. Mike Huckabee in 2008, for instance, drew a far more "way-out" crowd.
The crowd was supportive, even affectionate in its esteem for the man. They were there not to question the candidate, but to show him their support.
His appearance in Nashua underscored the fact that Ron Paul remains a gadfly. Agree with him or not, he is a critical spirit whose presence on the national scene is vital to maintaining the political dialogue that is essential to democracy.
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Public release date: 2-Dec-2011
Share ] Contact: Ferdie De Vega
Ferdinand.DeVega@moffitt.org
813-745-7858
H. Lee Moffitt Cancer Center & Research Institute
TAMPA, Fla. (Dec. 2, 2011) MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla. Their findings, recently appearing in Molecular Cancer Therapeutics, published by the American Association for Cancer Research, suggest that a badly needed new agent against sarcomas especially sarcomas affecting children may be at hand.
According to corresponding author Soner Altiok, M.D., Ph.D., sarcomas are rare forms of cancers and are comprised of more than 70 types. Approximately 10 percent of children with cancer are diagnosed with sarcomas, compared to eight percent of young adults and one percent of adults. While chemotherapy and radiation play a role in treating some sarcoma patients, escalations of treatment are unlikely to be tolerable, nor will they prolong survival, said the researchers.
"There is a great need for new agents to treat sarcomas and improve patient outcomes," said Altiok. "Toxicity from radiation and chemotherapy is high and response rates for patients with sarcomas are modest, with improvement and survival negligible."
Sarcomas are cancers that result from transformed cells in one of a number of tissues that develop from embryonic mesoderm. Sarcomas include tumors of bone, cartilage, fat, muscle, vascular and hematopoetic tissues. Sarcomas are different from carcinomas that originate in epithelial cells and result in more common cancers, such as breast, colon and lung cancers.
Researchers from Moffitt's Experimental Therapeutics Program and the Sarcoma Program collaborated in testing MK1775's ability to inhibit Wee1, a nuclear kinase known to be a regulator of cell size and an initiator of cell division, or mitosis. Wee1 is known to play a role in determining the timepoint at which mitosis begins. Loss of Wee1 can produce smaller than normal daughter cells. The researchers hypothesized that inhibition of Wee1 could also induce apoptosis, or programmed cell death in sarcoma tumors.
"Inhibition of the pathways critical to tumor cell survival by molecularly targeted therapy represents an opportunity to reverse the biological basis of tumor formation," explained Altiok. "We found that MK1775 treatment induces apoptopic cell death in four sarcoma cell lines at clinically relevant doses."
To further prove that inhibition of Wee1 by MK1775 leads to mitotic cell death in sarcomas cells, the researchers performed additional studies, including studies on sarcomas related to mutations, such as with the p53 gene. They also showed that MK1775 was an active inhibitor of Wee1 regardless of the p53 mutation status of the tumors in the cell lines tested.
"The cytotoxic effect of Wee1 inhibition on sarcoma cells appears to be independent of p53 mutation status following our testing sarcoma cell lines with different p53 mutations," he said. "All of them were highly sensitive to MK1775, suggesting that Wee1 inhibition may represent a novel approach in the treatment of sarcomas."
The researchers concluded that their laboratory tests on sarcoma cell lines suggest that MK1775 is effective as a monotherapy even in the cell lines that include p53 wild, p53 null and p53 mutant statuses.
Other studies have shown that MK1775 is a well-tolerated drug. No toxicity dose limit has been established, making MK 1775 a potential therapeutic agent for treating both adult and pediatric sarcoma patients.
"Our data has shown that MK1775 treatment causes cell death suggesting 'mitotic catastrophe,' a type of cell death that occurs during cell mitosis," concluded Altiok.
###
About Moffitt Cancer Center
Follow Moffitt on Facebook: www.facebook.com/MoffittCancerCenter
Follow Moffitt on Twitter: @MoffittNews
Follow Moffitt on YouTube: MoffittNews
Located in Tampa, Florida, Moffitt Cancer Center is an NCI Comprehensive Cancer Center a designation that recognizes Moffitt's excellence in research and contributions to clinical trials, prevention and cancer control. Moffitt currently has 14 affiliates in Florida, one in Georgia, one in Pennsylvania and two in Puerto Rico. Additionally, Moffitt is a member of the National Comprehensive Cancer Network, a prestigious alliance of the country's leading cancer centers, and is listed in U.S. News & World Report as one of "America's Best Hospitals" for cancer. Moffitt marks a very important anniversary in 2011 25 years committed to one mission: to contribute to the prevention and cure of cancer .
Media release by Florida Science Communications
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 2-Dec-2011 Share ] Contact: Ferdie De Vega
Ferdinand.DeVega@moffitt.org
813-745-7858
H. Lee Moffitt Cancer Center & Research Institute
TAMPA, Fla. (Dec. 2, 2011) MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla. Their findings, recently appearing in Molecular Cancer Therapeutics, published by the American Association for Cancer Research, suggest that a badly needed new agent against sarcomas especially sarcomas affecting children may be at hand.
According to corresponding author Soner Altiok, M.D., Ph.D., sarcomas are rare forms of cancers and are comprised of more than 70 types. Approximately 10 percent of children with cancer are diagnosed with sarcomas, compared to eight percent of young adults and one percent of adults. While chemotherapy and radiation play a role in treating some sarcoma patients, escalations of treatment are unlikely to be tolerable, nor will they prolong survival, said the researchers.
"There is a great need for new agents to treat sarcomas and improve patient outcomes," said Altiok. "Toxicity from radiation and chemotherapy is high and response rates for patients with sarcomas are modest, with improvement and survival negligible."
Sarcomas are cancers that result from transformed cells in one of a number of tissues that develop from embryonic mesoderm. Sarcomas include tumors of bone, cartilage, fat, muscle, vascular and hematopoetic tissues. Sarcomas are different from carcinomas that originate in epithelial cells and result in more common cancers, such as breast, colon and lung cancers.
Researchers from Moffitt's Experimental Therapeutics Program and the Sarcoma Program collaborated in testing MK1775's ability to inhibit Wee1, a nuclear kinase known to be a regulator of cell size and an initiator of cell division, or mitosis. Wee1 is known to play a role in determining the timepoint at which mitosis begins. Loss of Wee1 can produce smaller than normal daughter cells. The researchers hypothesized that inhibition of Wee1 could also induce apoptosis, or programmed cell death in sarcoma tumors.
"Inhibition of the pathways critical to tumor cell survival by molecularly targeted therapy represents an opportunity to reverse the biological basis of tumor formation," explained Altiok. "We found that MK1775 treatment induces apoptopic cell death in four sarcoma cell lines at clinically relevant doses."
To further prove that inhibition of Wee1 by MK1775 leads to mitotic cell death in sarcomas cells, the researchers performed additional studies, including studies on sarcomas related to mutations, such as with the p53 gene. They also showed that MK1775 was an active inhibitor of Wee1 regardless of the p53 mutation status of the tumors in the cell lines tested.
"The cytotoxic effect of Wee1 inhibition on sarcoma cells appears to be independent of p53 mutation status following our testing sarcoma cell lines with different p53 mutations," he said. "All of them were highly sensitive to MK1775, suggesting that Wee1 inhibition may represent a novel approach in the treatment of sarcomas."
The researchers concluded that their laboratory tests on sarcoma cell lines suggest that MK1775 is effective as a monotherapy even in the cell lines that include p53 wild, p53 null and p53 mutant statuses.
Other studies have shown that MK1775 is a well-tolerated drug. No toxicity dose limit has been established, making MK 1775 a potential therapeutic agent for treating both adult and pediatric sarcoma patients.
"Our data has shown that MK1775 treatment causes cell death suggesting 'mitotic catastrophe,' a type of cell death that occurs during cell mitosis," concluded Altiok.
###
About Moffitt Cancer Center
Follow Moffitt on Facebook: www.facebook.com/MoffittCancerCenter
Follow Moffitt on Twitter: @MoffittNews
Follow Moffitt on YouTube: MoffittNews
Located in Tampa, Florida, Moffitt Cancer Center is an NCI Comprehensive Cancer Center a designation that recognizes Moffitt's excellence in research and contributions to clinical trials, prevention and cancer control. Moffitt currently has 14 affiliates in Florida, one in Georgia, one in Pennsylvania and two in Puerto Rico. Additionally, Moffitt is a member of the National Comprehensive Cancer Network, a prestigious alliance of the country's leading cancer centers, and is listed in U.S. News & World Report as one of "America's Best Hospitals" for cancer. Moffitt marks a very important anniversary in 2011 25 years committed to one mission: to contribute to the prevention and cure of cancer .
Media release by Florida Science Communications
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2011-12/hlmc-mcc120211.php
Jason Reed / Reuters file
Women seem to prefer the white iPhone to the black model, according to new research.
By Suzanne Choney
How badly did many of us want the new iPhone 4S? Badly enough to break our contracts with wireless carriers and pay an early termination fee to get the phone, according to some new research.
Consumer Intelligence Research Partners surveyed 4S buyers between Oct. 31 and Nov. 10 and found that "45 percent said they had broken a contract with their current or previous carrier to buy or upgrade to the device. Of those, more than 70 percent paid an early termination fee greater than $100 to do so," according to AllThingsD.
AT&T, Verizon and Sprint charge a maximum early termination fee of $350.
From an initial response of 4,632 people, the research firm said?it surveyed 504 "qualified subjects" for its analysis about iPhone 4S buyers. Among its other findings:
Related stories:
Check out Technolog, Gadgetbox, Digital Life and In-Game on?Facebook,?and on Twitter, follow Suzanne Choney.
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Ten years ago today, George Harrison died at age 58. To mark the occasion, we've collected a few classic images of the legendary musician?and excerpted his bio from our friends over at Rolling Stone.
Juergen Vollmer / Getty Images
George Harrison in Hamburg, Germany, in April, 1961.
Known first as "The Quiet Beatle," George Harrison was a great songwriter who had the misfortune to be surrounded by two stone cold geniuses whose work often obscured his talents. Yet Harrison compositions such as "Something" and "While My Guitar Gently Weeps" are as good as anything the Beatles ever recorded. And with his solo debut All Things Must Pass, he stepped completely out of the shadows of his Beatle band mates to reveal himself a powerfully spiritual songwriter with an expansive sense of melody. Harrison was also a gifted, fluid guitarist and hugely influential in introducing the Beatles ? and, by extension, the entire Sixties generation ? to Eastern religion and musical influences.
Before all that, Harrison was a teen guitarist in thrall to Britain's 1950s skiffle revival ? a working class kid with a band called the Rebels. It was Paul McCartney, a schoolmate one year ahead of Harrison, who invited the 15-year-old to jam with the Quarrymen, a group led John Lennon. (Harrison had come three years behind Lennon at his previous school.) This band would become the Beatles ? and Harrison would himself become, like Lennon and McCartney, one of his generation's great seekers. His response to fame, however, was to direct that search inside of himself
Read the full bio here.
Popperfoto / Getty Images
Harrison on stage during The Beatles' 1964 tour of the United States.
Terry O'neill / Getty Images
Harrison attends a UNICEF gala in Paris in December 1967.
Terry O'neill / Getty Images
Harrison in 1975, on the grounds of his home, Friar Park, near Henley-on-Thames, south Oxfordshire, England.
John Livzey / Getty Images
What are your memories of Harrison? Were?you a fan of his music after The Beatles? Share your thoughts in the comments.
Related content:
TEHRAN (Reuters) ? Britain shut down the Iranian embassy in London and expelled all its staff on Wednesday, saying the storming of the British diplomatic mission in Tehran could not have taken place without some degree of consent from Iranian authorities.
Foreign Secretary William Hague also said the British Embassy in Tehran had been closed and all staff evacuated following the attack on Tuesday by a crowd that broke through gates, ransacked offices and burned British flags in a protest over sanctions imposed by Britain on the Tehran government.
It was the most violent incident so far as relations between the two countries steadily deteriorate due to Iran's wider dispute with the West over its nuclear program.
On top of its ban on British financial institutions dealing with Iran and its central bank last week, Britain has called for further measures and a diplomatic source said London would now support a ban on oil imports from the Islamic Republic.
Hague said Iranian ambassadors across the European Union had been summoned to receive strong protests over the incident. But Britain stopped short of severing ties with Iran completely.
"The Iranian charge (d'affaires) in London is being informed now that we require the immediate closure of the Iranian embassy in London and that all Iranian diplomatic staff must leave the United Kingdom within the next 48 hours," Hague told parliament.
"We have now closed the British embassy in Tehran. We have decided to evacuate all our staff and as of the last few minutes, the last of our UK-based staff have now left Iran."
It was the worst crisis between Britain and Iran since full diplomatic relations were restored in 1999, 10 years after Ayatollah Ruhollah Khomeini's fatwa to kill author Salman Rushdie for his book "The Satanic Verses."
Hague said it was "fanciful" to think the Iranian authorities could not have protected the British embassy, or that the assault could have taken place without "some degree of regime consent."
"This does not amount to the severing of diplomatic relations in their entirety. It is action that reduces our relations with Iran to the lowest level consistent with the maintenance of diplomatic relations," he added.
British Prime Minister David Cameron chaired meetings of the government's crisis committee on Tuesday night and again on Wednesday morning to decide London's response.
But mindful of the 1979 seizure of the U.S. embassy in Tehran, when radical students held 52 Americans hostage for 444 days, Britain waited till all its two dozen diplomatic staff and dependents had left the country to announce its move.
RIFT IN IRAN
"It's rock bottom as far as Anglo-Iranian relations are concerned," said Ali Ansari, director of the Institute for Iranian Studies at St Andrews University in Scotland. "The Iranians have a mountain to climb. I don't think they fully understand how difficult it is for them now."
Negotiations on Iran's nuclear program were now "dead," he said. "What you are moving into is a period of containment and quarantine. I don't think we are into a military confrontation, but we are into a period of containment and they (the West) are going to try and tighten the noose."
The attack also exposes widening rifts within Iran's ruling elite over how to deal with the increased international pressure as sanctions take their toll on the already stagnant economy.
The protest appeared to be a move by the conservatives who dominate parliament to force President Mahmoud Ahmadinejad to heed their demand to expel the British ambassador.
Ahmadinejad and his ministers have shown no willingness to compromise on their refusal to halt Iran's nuclear work but have sought to keep talks open to limit what sanctions are imposed.
The West believes the program is aimed at building a nuclear weapon, a charge Tehran strongly denies.
"This incident was planned by elements who are not opposed per se to negotiations but want to stop them merely because of their own petty political struggles," said Trita Parsi, a U.S.-based expert on Western-Iranian relations.
"The push to get the UK ambassador out came from parliament which is headed by Ali Larijani," Parsi said. "When Larijani was chief nuclear negotiator Ahmadinejad carried out a similar campaign against negotiations."
Conservative newspapers trumpeted the embassy seizure.
The daily Vatan-e Emrouz declared "Fox's den seized," referring to Britain's nickname "the old fox" which reflects a widely held view in Iran that London still wields great power behind the scenes in Iranian and international affairs.
While Iranian police at first did not stop the protesters storming the embassy gates, they later fired teargas to disperse them and freed six Britons held by demonstrators.
Iran's Foreign Ministry expressed its regret for the "unacceptable behavior of few demonstrators."
The protesters hit back, saying they had been "seeking to answer to the plots and malevolence of this old fox" and the Foreign Ministry should not sacrifice "the goals of the nation for diplomatic and political relations."
"We expected the police to be on the side of the students instead of confronting them," said a statement by a group calling itself the Islamic community of Tehran universities.
MORE SANCTIONS LIKELY
Britain imposed sanctions on the Iran central bank last week after a report by the U.N.'s International Atomic Energy Agency suggested Iran may have worked on developing a nuclear arsenal.
Iran, the world's fifth biggest oil exporter, says it only wants nuclear technology to generate electricity.
Britain has not backed a ban on Iranian oil imports, but that could now change, the diplomatic source told Reuters, and London will likely back a call by France to do just that and impose "sanctions on a scale that would paralyze the regime."
The United States, which cut diplomatic relations with Iran after its embassy was stormed in 1979, has not bought Iranian oil since the 1990s, but has not taken any measures against Iran's central bank. That would cripple Iran's economy as it would not be able to process payments for its vital oil exports.
(Additional reporting by Hossein Jaseb and Ramin Mostafavi in Tehran, Adrian Croft and Tim Castle in London, and Parisa Hafezi in Istanbul; Writing by Jon Hemming)
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