Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/193982115?client_source=feed&format=rss
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Tuesday, January 31, 2012
Top 5 foreign-language films
The Iranian film, 'A Separation,' has been met with widespread critical acclaim and an Academy Award nomination. Occasionally, foreign films score big at American box offices. Here are the all-time top-grossing foreign-language films in the US.
Source: Internet Movie Database, Yahoo! Movies
From: Taiwan. Box office receipts: $128 million. Two warriors meet their match in a teenage girl on their quest to recover a fabled stolen sword.
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/cq7fpUOhwPI/Top-5-foreign-language-films
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What are your views on what happens to your genomic information?
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 30-Jan-2012[ | E-mail |
Share ] Contact: Don Powell
press.office@sanger.ac.uk
44-122-349-6928
Wellcome Trust Sanger Institute
Survey aims to be the largest to capture public attitudes to sharing genomic results
Would you want to know about your genetic risk for hundreds of conditions all in one go, ranging from whether you have a higher than average risk from Alzheimer's disease or diabetes or whether you are sensitive to certain antibiotics or statins? How do you feel about researchers generating this information but not sharing it with you?
An ethics team from the Wellcome Trust Sanger Institute today launches an online survey to capture the views of as many people as possible: they hope it will be the largest collection of opinions gathered to date.It has been standard practice for many years to conduct genetic research anonymously and not share such findings with the research participants who provided the samples. However, there is now increasing pressure to change this approach.
"We need to understand what people want from whole genome testing," says Dr Anna Middleton, Ethics Researcher from the Wellcome Trust Sanger Institute. "Policy is being written worldwide on what researchers should share from genome studies and yet much of this is based on anecdote and intuition. We aim to address this by conducting an international study that asks members of the public, health professionals and researchers for their views."
Genetic analysis of a saliva or blood sample can now reveal elements of a person's past, present and future medical health.In whole genome studies, researchers can examine all 20,000 human genes in only a matter weeks to understand the genetic basis of disease.
An ethics team from the Wellcome Trust Sanger Institute in Cambridge, UK use film in an innovative online questionnaire to explore the ethical implications of whole genome research.
Participants in the survey need have no prior knowledge about genetics and anyone can participate (see www.genomethics.org). The study aims to be the largest of its kind in the world and will be used to guide policy on how genome research studies should be conducted. This survey is part of the proactive process of engaging with the public, before whole genome studies become part of health service practice.
"I have completed the ethics questionnaire as I am currently taking part in a whole genome study and I wanted my views to be heard" says Katrina Mcardle, mother of a child with developmental delay who is participating in a whole genome study.
"I am very keen to get a diagnosis for my son and the genome research may offer this, but I'm not sure I want to know lots of additional information about his future health that is unrelated to his diagnosis. Everyone should think about these issues and fill in this questionnaire."
"It is soon going to be cheaper and easier to look at all of a person's 20,000 genes in one go rather than searching for an individual gene, as currently happens," says Professor Anneke Lucassen, Consultant in Clinical Genetics, University of Southampton.
"This raises all sorts of ethical issues about what genetic results you share with people. Very soon this technology will be used in the NHS and we urgently need research that tells us what people want to know."
"This is a really exciting project using an innovative questionnaire and the integrated films really bring it to life," says Professor Mike Parker, Professor of Bioethics and Director of the Ethox Centre at University of Oxford. "The questionnaire asks for feedback on some difficult ethical issues and I will be encouraging everyone I know to participate."
###
Notes to Editors
Websites
The survey can be found at http://www.genomethics.org/
Funding
This programme is funded by the Health Innovation Challenge Fund and the Wellcome Trust Sanger Institute.
http://www.hicfund.org.uk/
The Wellcome Trust Sanger Institute is one of the world's leading genome centres. Through its ability to conduct research at scale, it is able to engage in bold and long-term exploratory projects that are designed to influence and empower medical science globally.
Institute research findings, generated through its own research programmes and through its leading role in international consortia, are being used to develop new diagnostics and treatments for human disease.
http://www.sanger.ac.uk
The Wellcome Trust is a global charitable foundation dedicated to achieving extraordinary improvements in human and animal health. We support the brightest minds in biomedical research and the medical humanities. Our breadth of support includes public engagement, education and the application of research to improve health. We are independent of both political and commercial interests.
http://www.wellcome.ac.uk
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 30-Jan-2012[ | E-mail |
Share ] Contact: Don Powell
press.office@sanger.ac.uk
44-122-349-6928
Wellcome Trust Sanger Institute
Survey aims to be the largest to capture public attitudes to sharing genomic results
Would you want to know about your genetic risk for hundreds of conditions all in one go, ranging from whether you have a higher than average risk from Alzheimer's disease or diabetes or whether you are sensitive to certain antibiotics or statins? How do you feel about researchers generating this information but not sharing it with you?
An ethics team from the Wellcome Trust Sanger Institute today launches an online survey to capture the views of as many people as possible: they hope it will be the largest collection of opinions gathered to date.It has been standard practice for many years to conduct genetic research anonymously and not share such findings with the research participants who provided the samples. However, there is now increasing pressure to change this approach.
"We need to understand what people want from whole genome testing," says Dr Anna Middleton, Ethics Researcher from the Wellcome Trust Sanger Institute. "Policy is being written worldwide on what researchers should share from genome studies and yet much of this is based on anecdote and intuition. We aim to address this by conducting an international study that asks members of the public, health professionals and researchers for their views."
Genetic analysis of a saliva or blood sample can now reveal elements of a person's past, present and future medical health.In whole genome studies, researchers can examine all 20,000 human genes in only a matter weeks to understand the genetic basis of disease.
An ethics team from the Wellcome Trust Sanger Institute in Cambridge, UK use film in an innovative online questionnaire to explore the ethical implications of whole genome research.
Participants in the survey need have no prior knowledge about genetics and anyone can participate (see www.genomethics.org). The study aims to be the largest of its kind in the world and will be used to guide policy on how genome research studies should be conducted. This survey is part of the proactive process of engaging with the public, before whole genome studies become part of health service practice.
"I have completed the ethics questionnaire as I am currently taking part in a whole genome study and I wanted my views to be heard" says Katrina Mcardle, mother of a child with developmental delay who is participating in a whole genome study.
"I am very keen to get a diagnosis for my son and the genome research may offer this, but I'm not sure I want to know lots of additional information about his future health that is unrelated to his diagnosis. Everyone should think about these issues and fill in this questionnaire."
"It is soon going to be cheaper and easier to look at all of a person's 20,000 genes in one go rather than searching for an individual gene, as currently happens," says Professor Anneke Lucassen, Consultant in Clinical Genetics, University of Southampton.
"This raises all sorts of ethical issues about what genetic results you share with people. Very soon this technology will be used in the NHS and we urgently need research that tells us what people want to know."
"This is a really exciting project using an innovative questionnaire and the integrated films really bring it to life," says Professor Mike Parker, Professor of Bioethics and Director of the Ethox Centre at University of Oxford. "The questionnaire asks for feedback on some difficult ethical issues and I will be encouraging everyone I know to participate."
###
Notes to Editors
Websites
The survey can be found at http://www.genomethics.org/
Funding
This programme is funded by the Health Innovation Challenge Fund and the Wellcome Trust Sanger Institute.
http://www.hicfund.org.uk/
The Wellcome Trust Sanger Institute is one of the world's leading genome centres. Through its ability to conduct research at scale, it is able to engage in bold and long-term exploratory projects that are designed to influence and empower medical science globally.
Institute research findings, generated through its own research programmes and through its leading role in international consortia, are being used to develop new diagnostics and treatments for human disease.
http://www.sanger.ac.uk
The Wellcome Trust is a global charitable foundation dedicated to achieving extraordinary improvements in human and animal health. We support the brightest minds in biomedical research and the medical humanities. Our breadth of support includes public engagement, education and the application of research to improve health. We are independent of both political and commercial interests.
http://www.wellcome.ac.uk
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-01/wtsi-way012712.php
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Monday, January 30, 2012
Baylor still No. 1 in AP women's basketball poll (AP)
Baylor remains the unanimous No. 1 choice in The Associated Press women's college basketball poll.
The Lady Bears received all the first-place votes Monday for the ninth straight week after routing Oklahoma and Kansas. Baylor visits Missouri and Kansas State this week.
Notre Dame, Connecticut, Stanford and Duke followed the Lady Bears. Connecticut and Duke play each other on Monday night. Kentucky was sixth. Miami, Tennessee, Maryland and Green Bay round out the first 10. It is the highest ranking ever for the Phoenix, who along with Baylor are the only unbeaten teams left in Division I.
Georgia Tech entered the poll for the first time this season at No. 24. The Yellow Jackets host N.C. State on Thursday.
DePaul dropped out of the Top 25.
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Sunday, January 29, 2012
Saturday, January 28, 2012
Divorce and Pets | More People Choose Animals Over Money ...
Parents of people children know that they have a 50% chance of needing a ?What happens if we split? plan. They may not discuss it, they may not let themselves think about it, but I bet you, in the back of every parent?s mind is the ?What happens if?.? thought.
Personally, I don?t think that it?s all that crazy. Again, the divorce rate is roughly 40-50% in our country. I have friends who state, prior to marriage, that their future spouse is ?The one or the first one.? If you ignore marital status and just look at long-term committed relationships, chances are you still have roughly the same potential split rate. There?s just no getting around it anymore, any relationship has a roughly 50% chance of ending.?
Pet parents also may not discuss or let themselves think about ?What if?? but I promise you, it?s there. According to a survey of 1,500 pet owners by PetMD, ?90% of pet owners would fight more passionately for their pets than for money in a divorce.? Even more telling is this information released by?Michigan State University College of Law:??Because pets are becoming such a big part of our lives, some courts ? ?are willing to treat pets more like children? Courts have considered the best interest of the pets in determining who gets custody of them. They have also awarded shared custody, visitation, and alimony payments to the owners.?
What about you?? As pet owner (or pet parent, if you prefer), a people parent, or both, what do you think about having a ?What if?? plan?? Do you have one?? Have you and your spouse or significant other discussed ?What if??
?
Category: Features, Pets
Source: http://www.primeparentsclub.com/2012/01/27/divorce-and-pets-more-people-choose-animals-over-money/
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Friday, January 27, 2012
Jennifer Love Hewitt Strips Down to Promote The Client List [Video]
Okay, okay, we'll watch The Client List.
In a new video to promote the Lifetime original series - which centers on a broke Texas housewife who takes over a brothel - star/executive producer Jennifer Love Hewitt takes off a great deal of clothing and writhes all around, surrounded by half-naked men.
Her business is your pleasure, the tagline reads. And - GULP! - the show is not kidding. Sit back now, fellas, press Play and prepare a cold shower immediately afterwards. You're gonna need it:
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Rihanna to UK fashion newbies: Dress me up (AP)
LONDON ? Rihanna has found a unique way of getting some new stage outfits.
The musical superstar from Barbados will be hunting for undiscovered design talent in Britain on a new TV show ? as yet unnamed ? in which she will be the executive producer and the star.
Sky Living HD announced Thursday it has commissioned media company Twenty Twenty to make the series and say Rihanna will be working mainly behind the scenes.
Hosting duties will go to another pop name, Nicola Roberts from the U.K. group Girls Aloud.
Together they will challenge fashion newcomers to create stage gear for musicians and celebrities ? with the final task to dress Rihanna for her July 8 performance at the Wireless music festival in London's Hyde Park.
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Thursday, January 26, 2012
Disgust?s Evolutionary Role Is Irresistible to Researchers
[unable to retrieve full-text content]What disgusts humans is proving irresistible to researchers exploring the evolutionary value of revulsion.
Source: http://feeds.nytimes.com/click.phdo?i=4c22afce19001fb6a00713f49bdf7006
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Protester in Bahrain dies after arrest (AP)
MANAMA, Bahrain ? Bahrain authorities say a detainee has died after being taken into custody during clashes between security forces and Shiite-led protesters.
Thursday's statement by the Interior Ministry says public prosecutors are investigating the death. About 40 people have died in nearly a year of nonstop unrest between Bahrain's Sunni monarchy and the island kingdom's majority Shiites seeking a greater voice in government and security affairs.
The brief statement gave no further details on the death, but said the detainee was hospitalized and accused of "vandalism" during widespread demonstrations on Wednesday.
Bahrain is home to the U.S. Navy's 5th Fleet.
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Wednesday, January 25, 2012
Cyprus police charge ex-ministers in fatal blast
NICOSIA, Cyprus (AP) ? Cyprus police filed criminal charges against two former Cabinet ministers over last year's explosion of seized Iranian munitions that killed 13 people and touched off a political crisis, a senior police official said Tuesday.
The official said the charges against ex-Foreign Affairs Minister Markos Kyprianou and ex-Defense Minister Costas Papacostas include negligence causing death. The official spoke on condition of anonymity because of the sensitivity of the matter. Defendants convicted of that charge can be jailed for up to four years.
State-run CyBC television said the two men also face the more serious charge of manslaughter which carries a maximum life sentence.
Both Kyprianou and Papacostas told CyBC that they deny all charges.
Kyprianou said he believed the decision to prosecute him was politically motivated. "I consider it as an attempt to distract public opinion and to find a scapegoat," he said.
Papacostas said he looks forward to setting the record straight in court.
The
police official said unidentified charges also have been filed against three senior army officers and three fire department officials regarding the deaths.
Kyprianou and Papacostas resigned after the July 11, 2011, blast, which wrecked the island's main power station and triggered weeks of street protests calling for President Dimitris Christofias' resignation.
A public inquiry into the explosion said he was mainly to blame for the events that led to the explosion. Christofias rejected the inquiry's nonbinding findings.
The munitions packed in some 98 containers were confiscated in February 2009 from a Cypriot-flagged ship suspected of transporting it from Iran to Palestinian militants in Gaza through Syria in breach of a United Nations ban on Iranian arms exports.
The containers had been left piled in an open field inside the base, despite warnings from military officials that the munitions could spontaneously ignite as a result of their exposure to the elements.
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Reporters can now bring gadgets to House chamber
Tuesday's State of the Union address will be the first time reporters will be able to bring their electronic devices into the House gallery, according to a post in Roll Call. Photography and video won't be allowed, but if all goes well, electronic reporting will be permitted going forward.
There are, of course, a number of concerns: Reporters can't make calls, and phones must be completely silent ??even vibrate mode is prohibited. And reporters will be "closely monitored" to ensure there are no egregious (and potentially embarrassing) infractions.
The experiment will continue after the State of the Union. The House of Representatives will allow reporters to bring gadgets for the duration of the current session of Congress, and will evaluate whether or not to continue after that.?
For more on the new rule, and the House's on-again, off-again relationship with electronic gadgets, check out the Roll Call piece.
Be sure to catch the State of the Union tonight at 9 p.m. ET, right here at NBC Politics on msnbc.com.
More on the intersection of politics and technology:
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Tuesday, January 24, 2012
Reno wildfire that destroyed 29 homes contained
Chris Watts cries after pulling his grandmother's coffee mug out of the rubble of her home Saturday, Jan. 21, 2012, in Pleasant Valley, south of Reno, Nev. Authorities confirmed that the body of June Hargis, 93, was found in the aftermath of Thursday's brush fire, but her cause of death has not been established, so it's not known if it was fire related. The Watts family also lost their home, barn and three horses. (AP Photo/Cathleen Allison)
Chris Watts cries after pulling his grandmother's coffee mug out of the rubble of her home Saturday, Jan. 21, 2012, in Pleasant Valley, south of Reno, Nev. Authorities confirmed that the body of June Hargis, 93, was found in the aftermath of Thursday's brush fire, but her cause of death has not been established, so it's not known if it was fire related. The Watts family also lost their home, barn and three horses. (AP Photo/Cathleen Allison)
Jeannie Watts, left, looks through the rubble of her barn for the bodies of her three horses on Saturday, Jan. 21, 2012, after her home in Pleasant Valley, south of Reno, Nev., was destroyed in Thursday's brush fire. Family friend Brenda Moore is at right. (AP Photo/Cathleen Allison)
Comforted by neighbors, Jeannie Watts, left, stands Saturday, Jan. 21, 2012, outside the rubble where her mother, June Hargis, 93, died in Thursday's brush fire in Pleasant Valley, south of Reno, Nev. The family also lost their home, their barn and three horses. Authorities confirmed that Hargis' body was found in the fire's aftermath, but her cause of death has not been established, so it's not known if it was fire related. (AP Photo/Cathleen Allison)
Standing in front of the rubble of her home Saturday, Jan. 21, 2012, Jeannie Watts holds a picture of herself and her mother, June Hargis, who died Thursday as a wind-driven brush fire burned through Pleasant Valley, south of Reno, Nev. Authorities confirmed that the body of Hargis, 93, was found in the fire's aftermath, but her cause of death has not been established, so it's not known if it was fire related. (AP Photo/Cathleen Allison)
Patrick, left, and Jeannie Watts, center, are consoled by neighbors at their Pleasant Valley home, south of Reno, Nev., on Saturday, Jan. 21, 2012. Their home was one of 29 destroyed by a wind-driven brush fire that raced through the area on Thursday. Authorities confirmed that the body of Jeannie Watts' mother, June Hargis, 93, was found in the fire's aftermath, but her cause of death has not been established, so it's not known if it was fire related. (AP Photo/Cathleen Allison)
RENO, Nev. (AP) ? The wildfire that destroyed 29 homes near Reno is contained. Thousands of evacuees are back home. And the family of the woman found dead says there's no point in prosecuting the remorseful man who accidentally started it.
Fire officials declared the blaze contained Saturday after a storm brought precipitation that the region hasn't seen in months. All evacuations were lifted and U.S. 395 reopened through the 3,200-acre fire zone.
But in addition to two inches of rain, the storm also brought another challenge for emergency workers. Officials fear its potential for causing flooding in burned areas, after one of the driest winters in Reno history.
"I'm confident we'll be able to respond successfully if necessary," Washoe County Manager Katy Simon said, adding that hydrologists and officials were monitoring the situation.
The blaze erupted shortly after noon on Thursday and raced quickly through the dry countryside, propelled by wind gusts of 82 mph. At its height, the fire forced evacuation calls for some 10,000 people.
The blaze was very similar to a wildfire that destroyed 30 homes in Reno in mid-November.
June Hargis, 93, was found dead in a studio apartment next to her daughter's home in Washoe Valley, where the fire started. Washoe County Sheriff Mike Haley said her cause of death has not been established, so it's not known if it was fire related. No other fatalities or major injuries were reported.
Her family said Saturday that there was no point in prosecuting the man who admitted accidentally starting it by improperly discarding fireplace ashes outside his home.
Authorities have described man, whose name was not released, as being extremely remorseful.
Haley said that prosecutors will have to give the case a lot of deliberation. "The fact he came forward and admitted it plays a role. But so does the massive damage and loss of life," he said Friday. "It's a balancing act."
Hargis's son, Jim Blueberg, 68, told The Associated Press Saturday that he didn't think filing criminal charges against the elderly man "would do any good."
"The man had the courage to come up and say he did this. He's remorseful. I think he's punished himself enough. It was a silly, stupid mistake to make, there's no doubt about that. But I just want him to know I forgive him, and my heart goes out to him," he said.
His sister, Jeannie Watts, 70, had returned home from an errand to find the apartment next door and a barn with three horses inside engulfed in flames. She agreed that there was probably no need to file charges against the man.
"What good is that going to do? Everything is already gone," Watts said.
"He'll pay the rest of his life for that," she added.
Watts said it took only about 15 minutes for her three-bedroom farmhouse to burn down, though the fire reached her mother's apartment and the barn first. She said her mother appeared to be mentally alert when she last saw her.
"Before I got home, my son told her, 'Get your stuff and get out of here,'" Watts told the AP. "She said to him, 'Well, I can smell smoke but I can't see any fire,' and she went back inside. She probably suffocated from the smoke because it was so thick."
She said that when she got home, she shouted: "Where's my mom? Where's my mom?"
"The firefighters didn't know," she said. "Later, an official came to me and said, 'Yes, she was in (the burned studio).' Then they called the coroner. I was just crying and screaming. I still can't believe it."
Blueberg said the death of their mother comes after his sister had been through "one hard knock after another" in recent years.
The fire left her financially strapped, with virtually no earthly possessions, he said. "She told me the other day, 'All I have is my purse, that's all I have,'" he said.
She and her husband, Pat, met with an insurance agent on the property. In addition to the destroyed buildings, three horses in her barn died, though firefighters rescued all five dogs from her home.
"My stomach is up in the air," Watts said. "I want to cry and I can't. I want to say, 'Why us? Why anybody? Why does anything like this have to happen to anybody?"
___
Associated Press writers Scott Sonner in Reno, Michelle Rindels in Las Vegas and Sandra Chereb in Carson City contributed to this report.
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La Jolla Institute scientist takes quest to conquer Type 1 diabetes to the next level
Public release date: 23-Jan-2012[ | E-mail |
Share ] Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Renowned researcher to lead new translational center
SAN DIEGO (January 23, 2012) La Jolla Institute scientist Matthias von Herrath, M.D., a world leader in basic research on type 1 diabetes, has long dreamed of seeing his discoveries translated into new therapies to better treat this serious and chronic disorder. Dr. von Herrath may soon get his chance as head of a new translational type 1 diabetes center to be opened in Seattle in 2012 by Novo Nordisk, a global healthcare company specializing in diabetes care. Dr. von Herrath will continue to lead his vibrant and renowned research program at the La Jolla Institute for Allergy & Immunology on a part-time basis.
"We are excited by the opportunities that this dual appointment will provide Dr. von Herrath to take his discoveries to the next level clinical development," said Mitchell Kronenberg, Ph.D., La Jolla Institute president & chief scientific officer. "As a nonprofit biomedical research institute, our mission is to find the molecular causes of diseases, with the hope that our discoveries will one day be translated into new and better therapies. This is an important step toward that goal."
Dr. Jacob Sten Petersen, Novo Nordisk corporate vice president, said the new translational center will be based on an innovative strategic concept to move early stage discovery projects rapidly from mouse models into small clinical exploration trials in type 1 diabetes patients. "The primary goal of this initiative is to find new, innovative ways to treat people with type 1 diabetes," he said, adding that the Center is planned to open this summer.
The company sought Dr. von Herrath to lead the Center due to his stellar record in type 1 diabetes research. "Dr. von Herrath is generally regarded as one of the top researchers in the world in type 1 diabetes," said Dr. Petersen. "He has made several key advances and is the kind of dedicated, talented researcher that can fuel true innovation in type 1 diabetes treatment." Dr. von Herrath is the recipient of the Juvenile Diabetes Research Foundation's prestigious Scholar Award and in 2008 received the Outstanding Scientific Achievement Award from the American Diabetes Association.
The Center will focus on the development of type 1 diabetes immunotherapies, an area where Dr. von Herrath has specialized expertise. "My dream has always been to see the most promising immune-based interventions translated into better treatments for patients with diabetes," he said. "As head of the translational center, I will have an opportunity to pursue this dream, as well as forge new public-private collaborations to access other novel research ideas for potential development into better treatment options for people with type 1 diabetes."
Dr. Kronenberg said Novo Nordisk has the kind of strong biopharmaceutical development infrastructure that is necessary to take discoveries from research laboratories, into human clinical trials, and, if successful, into approved drugs. "By establishing this relationship with Novo Nordisk, Dr. von Herrath is accelerating an important and complementary process that is strongly supported by this Institute; one that moves discoveries toward becoming treatments available to patients," he said. "We are pleased that Dr. von Herrath has entered into this exciting endeavor, while at the same time maintaining his laboratory and research efforts at our Institute. Clearly, this type of arrangement is a win-win for the scientific community and for patients."
Based in Denmark, Novo Nordisk has a longstanding history in type 1 diabetes treatment and markets several drugs for diabetes sufferers worldwide. Globally, about 6,000 people work on the company's research and development activities.
###
About La Jolla Institute
Founded in 1988, the La Jolla Institute for Allergy & Immunology is a biomedical research nonprofit focused on improving human health through increased understanding of the immune system. Its scientists carry out research seeking new knowledge leading to the prevention of disease through vaccines and the treatment and cure of infectious diseases, cancer, inflammatory and autoimmune diseases such as rheumatoid arthritis, type 1 (juvenile) diabetes, Crohn's disease and asthma. La Jolla Institute's research staff includes more than 150 Ph.D.s and M.D.s. To learn more about the Institute's work, visit www.liai.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 23-Jan-2012[ | E-mail |
Share ] Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Renowned researcher to lead new translational center
SAN DIEGO (January 23, 2012) La Jolla Institute scientist Matthias von Herrath, M.D., a world leader in basic research on type 1 diabetes, has long dreamed of seeing his discoveries translated into new therapies to better treat this serious and chronic disorder. Dr. von Herrath may soon get his chance as head of a new translational type 1 diabetes center to be opened in Seattle in 2012 by Novo Nordisk, a global healthcare company specializing in diabetes care. Dr. von Herrath will continue to lead his vibrant and renowned research program at the La Jolla Institute for Allergy & Immunology on a part-time basis.
"We are excited by the opportunities that this dual appointment will provide Dr. von Herrath to take his discoveries to the next level clinical development," said Mitchell Kronenberg, Ph.D., La Jolla Institute president & chief scientific officer. "As a nonprofit biomedical research institute, our mission is to find the molecular causes of diseases, with the hope that our discoveries will one day be translated into new and better therapies. This is an important step toward that goal."
Dr. Jacob Sten Petersen, Novo Nordisk corporate vice president, said the new translational center will be based on an innovative strategic concept to move early stage discovery projects rapidly from mouse models into small clinical exploration trials in type 1 diabetes patients. "The primary goal of this initiative is to find new, innovative ways to treat people with type 1 diabetes," he said, adding that the Center is planned to open this summer.
The company sought Dr. von Herrath to lead the Center due to his stellar record in type 1 diabetes research. "Dr. von Herrath is generally regarded as one of the top researchers in the world in type 1 diabetes," said Dr. Petersen. "He has made several key advances and is the kind of dedicated, talented researcher that can fuel true innovation in type 1 diabetes treatment." Dr. von Herrath is the recipient of the Juvenile Diabetes Research Foundation's prestigious Scholar Award and in 2008 received the Outstanding Scientific Achievement Award from the American Diabetes Association.
The Center will focus on the development of type 1 diabetes immunotherapies, an area where Dr. von Herrath has specialized expertise. "My dream has always been to see the most promising immune-based interventions translated into better treatments for patients with diabetes," he said. "As head of the translational center, I will have an opportunity to pursue this dream, as well as forge new public-private collaborations to access other novel research ideas for potential development into better treatment options for people with type 1 diabetes."
Dr. Kronenberg said Novo Nordisk has the kind of strong biopharmaceutical development infrastructure that is necessary to take discoveries from research laboratories, into human clinical trials, and, if successful, into approved drugs. "By establishing this relationship with Novo Nordisk, Dr. von Herrath is accelerating an important and complementary process that is strongly supported by this Institute; one that moves discoveries toward becoming treatments available to patients," he said. "We are pleased that Dr. von Herrath has entered into this exciting endeavor, while at the same time maintaining his laboratory and research efforts at our Institute. Clearly, this type of arrangement is a win-win for the scientific community and for patients."
Based in Denmark, Novo Nordisk has a longstanding history in type 1 diabetes treatment and markets several drugs for diabetes sufferers worldwide. Globally, about 6,000 people work on the company's research and development activities.
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About La Jolla Institute
Founded in 1988, the La Jolla Institute for Allergy & Immunology is a biomedical research nonprofit focused on improving human health through increased understanding of the immune system. Its scientists carry out research seeking new knowledge leading to the prevention of disease through vaccines and the treatment and cure of infectious diseases, cancer, inflammatory and autoimmune diseases such as rheumatoid arthritis, type 1 (juvenile) diabetes, Crohn's disease and asthma. La Jolla Institute's research staff includes more than 150 Ph.D.s and M.D.s. To learn more about the Institute's work, visit www.liai.org.
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Source: http://www.eurekalert.org/pub_releases/2012-01/ljif-lji012012.php
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Monday, January 23, 2012
LG?s Quad-Core 2012 Flagship Leaks: The Poorly Code-Named X3
Other than the LG Spectrum, LG didn't have much to show off by way of phones at this year's CES show. But that doesn't mean that something special isn't in the works. In fact, Pocketnow reports that LG's 2012 flagship will run a Tegra 3 quad-core chipset and go by the name X3, at least for now. The phone likely won't show up on store shelves until spring or summer, but we should hear an announcement (including a retail name) come Mobile World Congress in February.Source: http://feedproxy.google.com/~r/Techcrunch/~3/JrwKy-kFfDc/
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Pakistan: Bad heart drugs suspected in 25 deaths
ISLAMABAD (AP) ? A government health official says bad drugs are suspected of killing at least 25 heart patients over the last month in the Pakistani city of Lahore.
Javed Akram said Monday that 100 other heart patients who had taken the same medicine have been admitted to hospitals in the city and 50 of them are in critical condition.
Akram is leading a probe into the deaths set up by the government of Punjab province, where Lahore is the capital. He said the suspected drugs were given free to patients by the state-run Punjab Institute of Cardiology.
Akram said patients developed red spots on their skin within days of taking the medicine that is suspected of killing them.
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Sunday, January 22, 2012
Solar Flare May Spark Weekend Northern Lights Show (SPACE.com)
A powerful flare erupted from the sun Thursday (Jan. 19), unleashing a plasma wave that may supercharge the northern lights for skywatchers in high latitudes this weekend.
The solar flare occurred at about 11:30 am EST (1600 GMT) and touched off a massive solar explosion ? known as a coronal mass ejection ? aimed at Earth, space weather experts and officials said. The charged particles from the sun explosion should reach Earth by Saturday night (Jan. 21), and could amp up northern lights displays when they hit the upper atmosphere.
"Forecasters say strong geomagnetic storms are possible when the cloud arrives during the late hours of Jan. 21st. High-latitude (and possibly middle-latitude) sky watchers should be alert for auroras this weekend," the skywatching website Spaceweather.com announced in an alert.
Several space telescopes recorded photos and video of the solar flare, including NASA's Solar Dynamics Observatory (SDO) and the Solar Heliospheric Observatory (SOHO). [Photo and video of the solar flare]
According to the Space Weather Prediction Center maintained by NOAA, Thursday's solar flare erupted from an active sunspot group called Region 1401. Another solar hotspot, called Region 1402, is also fired off a flare, the center reported.?
Auroras occur when charged particles from the sun interact with Earth's upper atmosphere, releasing visible light in the process. The particles are funneled toward Earth's polar regions by the planet's magnetic field, with the northern auroral displays known as the aurora borealis, or northern lights. The southern counterpart is called the aurora australis, or southern lights.?
Thursday's solar flare rated as a powerful M2-class sun storm on the scale used by astronomers to measure flare strength. M-class storms are powerful, but mid-range, types of solar flares. They fall between the weaker C-class flares and the most powerful X-class solar storms, which can pose a threat to satellites and astronauts in orbit, cause widespread communications interference and damage infrastructure on Earth when aimed directly at the planet.
SDO mission scientists have said that sunspot group 1401 has been unleashing solar flares almost daily as the sun's rotation slowly turned the solar hotspot toward Earth in recent days. On Wednesday (Jan. 18), the region unleashed an M1.7-class solar flare, they said in a Twitter post.
The sun is currently in the middle of an active phase of its 11-year solar weather cycle. The current sun storm cycle, called Solar Cycle 24, is expected to peak in 2013, NASA scientists have said.
Editor's note: If you snap an amazing northern lights photo, or other skywatching image, and would like to share it for a possible story or gallery, please contact managing editor Tariq Malik at?tmalik@space.com.
Follow SPACE.com for the latest in space science and exploration news on Twitter?@Spacedotcom?and on?Facebook.
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Saturday, January 21, 2012
Insight: Freed prisoners add momentum, risks to Myanmar reform (Reuters)
YANGON (Reuters) ? Buddhist monk Shin Gambira endured solitary confinement, beatings and sleep deprivation in Myanmar's prisons for his leading role in the 2007 "Saffron Revolution" -- peaceful protests that were crushed by the country's military.
Finally free at a monastery on the outskirts of Myanmar's main city of Yangon, about the worst he will say of his captors is that they were "very rude and cruel".
"Don't let me elaborate on it. Let bygones be bygones," the 33-year-old former protest leader said of his ordeal, following his release last week with about 300 other political prisoners.
Interviews by Reuters with more than a dozen of the newly released prisoners in recent days reveal a similar remarkable lack of bitterness toward their captors after years of imprisonment and torture for their beliefs. They described overcrowded cells at the notorious Insein detention center, watching a fellow inmate die from a lack of medical care, and routine deprivation of water and sleep among other abuses.
But nearly all said they backed opposition leader Aung San Suu Kyi's decision to place trust in the government's reform pledges and take part in April by-elections that could give her National League for Democracy (NLD) party a vital foothold in parliament, part of dramatic changes underway in the former Burma.
"This is Daw Aung San Suu Kyi trying in the most non-violent way to work for the country's transition to democracy. We support this," said Htay Kywe, a leader of the "88 generation" students group, referring to Suu Kyi by her honorific title.
Htay Kywe and many other prisoners released last week helped to lead pro-democracy protests in 1988 in which thousands of demonstrators were killed by soldiers.
The largest release yet of high-profile dissidents promises to speed up the national reconciliation process and provides a powerful argument for the United States and other Western nations to lift economic sanctions against the impoverished but resource-rich country.
Business executives, mostly from Asia, have swarmed into the commercial capital, Yangon, in recent weeks to hunt for investment opportunities in the country of 60 million people, one of the last frontier markets in Asia. Myanmar is also at the center of a struggle for strategic influence as the United States sees a chance to expand its ties there and balance China's fast-growing economic and political clout in the region.
Myanmar has thawed astonishingly quickly in the past year.
The government has begun peace talks with ethnic rebels, relaxed its strict media censorship, allowed trade unions and protests, and showed signs of pulling back from the powerful economic and political orbit of its giant neighbor China. It was rewarded last November when Hillary Clinton made the first visit to the country by a U.S. secretary of state since 1955.
The exact number of political detainees still locked up in Myanmar's prisons remains in doubt. But the opposition and government agree it is now in the hundreds. That may not be much higher than some of its Southeast Asian neighbors, making it hard for countries to argue in favor of maintaining sanctions.
Communist Vietnam, which has a bilateral trade deal with Washington, for instance, probably has political prisoners "in the hundreds", said Bangkok-based Phil Robertson of Human Rights Watch.
RECONCILIATION RISKS
Still, the interviews with the former prisoners in Myanmar reveal an undercurrent of skepticism about the government's true intentions and an impatience for more concrete democratic reforms.
Many also expressed concern that Suu Kyi risks weakening her powerful political capital if, as some believe, she takes a ministerial role as part of the reconciliation process. That could point to future tensions within the opposition and complicate the reform process if the pace of change stutters in coming months.
Last week's release brings the number of political detainees freed since last May to 645, according to the Assistance Association for Political Prisoners. This number represents a significant body of high-profile dissidents who are likely to influence internal opposition debate.
The latest group, ranging from the former head of military intelligence to a musician who penned songs about Suu Kyi, rejoin the political scene just as the government and opposition engage in a delicate, high-stakes dance toward reconciliation.
The views of this respected group of dissident opinion-formers are a vital gauge of support for Suu Kyi's leap of faith in engaging with the nominally civilian government. If they clamor for faster reforms than the government or Suu Kyi is comfortable with, for example, it could risk a backlash from military hardliners who many observers believe are eager for a chance to reverse the democratization process.
"We shouldn't settle for the present situation, there is a lot to be done," said Gambira, the freed Buddhist monk.
"Since the people were deprived of everything under a brutal regime for about 50 years they tend to be satisfied when they get something, compared with nothing in the past. I'd like to stress there is no room for complacency at present."
Skeptics worry that Nobel Peace Prize winner Suu Kyi, herself released from house arrest in late 2010, could be walking into a trap, handing valuable international legitimacy to the government before any fundamental changes in Myanmar's political system are secured. The United States, which has made the freeing of political prisoners a condition for lifting sanctions, said after the latest release it would exchange ambassadors with Myanmar for the first time in 20 years.
But Myanmar's generals still effectively control parliament after a deeply flawed 2010 election and the constitution, written in 2008, guarantees the military's dominant role in politics.
"Concerning the overall political situation, I'm not that optimistic. I'll put it at about 55 percent," said Khun Tun Oo, chairman of an ethnic Shan party allied to Suu Kyi's NLD and who was released after nearly seven years in jail.
He plans to re-register his party but not to run in the upcoming by-elections, which many believe would legitimize the 2010 elections widely seen as a sham.
"No doubt she (Suu Kyi) will have her say but I'm not sure she will be able to change the constitution ... the military is in a position to put a spanner in the works since they have the constitutional right."
MEDITATION AND GARDENING
Khun Tun Oo appears to have suffered relatively little torture in prison, but others were less fortunate.
Sithu Zeya, a 22-year-old journalist for exiled media outlet Democratic Voice of Burma, said he had to drink toilet water for the first five days in prison in 2010 and went without sleep for 15 days. He was regularly beaten and saw an old man in his cell die from breathing difficulties after medical help failed to arrive on time. Like many fellow prisoners, he found solace in meditation and limited chances to read and play sports.
"We have been released because foreign countries demanded it, not because they (the government) think it was wrong to have political prisoners," the former biology student told Reuters.
He said he supported Suu Kyi's participation in the elections but worried she would be a weaker voice as a lawmaker. "I don't want that to happen," he said.
Perhaps the most remarkable figure to emerge from detention last week was former military intelligence chief and prime minister Khin Nyunt, whose purge from the government in 2004 turned him overnight from one of the regime's most powerful figures into a lowly prisoner.
Ironically, he coped with his seven years under house arrest on charges of corruption in much the same way as Suu Kyi -- meditating every day and tending to his garden.
Deprived of financial support, he said he and his wife scraped a living by selling orchids from their garden and later by selling his clothes, including traditional silk "longyi" garments he had received as gifts when he was thought to be the regime's third most powerful official.
"It's embarrassing to tell this but this is the truth," he told Reuters at his home and former prison.
He ruled out a return to politics, saying he wanted to focus on his religious practice. Asked if he thought President Thein Sein could operate independently in his dealings with Suu Kyi, he smiled. "I think so, but I don't know for sure."
A concern repeatedly voiced by the freed dissidents was that the revered Suu Kyi could jeopardize her iconic and clean status by being drawn into a flawed political system.
"I'm fully confident in Aunty Suu's leadership. She's a national leader," said 32-year-old blogger Nay Phone Latt, who was picked up by security forces at a Yangon caf? in January 2008. "But I'm really worried that she will become a cabinet member. Then she might lose contact with the party."
Win Min, a Burmese political scientist at Harvard University and a student protester in the 1988 uprising, said the newly released 88 generation faced a challenge to push for genuine reforms without giving hardliners an excuse to crack down.
"At this critical juncture, 88 generation leaders may want to work in a space between the politics of struggle and normal politics to encourage the continuation of reform in a non-threatening way to the hardliners," he said.
"For the moderates in the government, the challenge is how to work with the opposition and the 88 generation leaders to improve the economy on the grassroots level."
"PEOPLE STILL SUFFERING"
Many freed prisoners cautioned that ordinary Burmese, struggling in poverty and often at the mercy of authoritarian local officials, have yet to benefit from the changes.
"They keep saying the higher authorities have changed, but the officials on the ground have not changed so the people are still suffering," said Zeya, the journalist. "The reforms have yet to make positive impacts on the general public so I can't say they are successful just yet."
A near-term source of tension is likely to be the fate of the political prisoners who remain behind bars.
Of the 604 political prisoners claimed by the NLD, the government only released 302 by its count, saying that 107 had already been released, others had been double-counted or died and that 128 would not be freed because they had committed serious crimes such as using explosives.
"I want the government to carry out more meaningful changes like releasing the remaining prisoners of conscience, which really will benefit the people and the country," said Nilar Thein, a female leader of the 88 generation whose latest arrest was in 2008.
For her, though, the most promising sign of real change in Myanmar was the confident smiles that greeted her on her recent release from detention. "I was really encouraged to see the courage and confidence on the faces of the people," she said.
"There is more transparency then before. It was a big difference from my previous releases."
(Additional reporting by Martin Petty in Bangkok.; Writing by Stuart Grudgings; Editing by Jason Szep and Mark Bendeich)
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Lawmakers flip on piracy bills protested on Web (Reuters)
(Reuters) ? Some members of Congress switched sides to oppose antipiracy legislation as protests blanketed the Internet on Wednesday, turning Wikipedia dark and putting black slashes on Google and other sites as if they had been censored.
Content providers who favor the anti-piracy measures, such as Hollywood and the music industry, were scrambling to win back public opinion and official support.
Wikipedia, the world's free online encyclopedia, shut down for a day. Google and others used the black censorship bars to draw attention to what had until recently been an obscure and technical legislative proposal to curb access to overseas websites that traffic in stolen content or counterfeit goods.
Many of the sites participating in the blackout urged their users to contact their legislators on the issue, a plea that brought quick results.
Several sponsors of the legislation, including Senators Roy Blunt, Chuck Grassley, Orrin Hatch and John Boozman and Marco Rubio, said they were withdrawing their support. Some blamed Senate Majority Leader Harry Reid for rushing the Senate version of the bill.
Meanwhile, friends of the bills stepped up their efforts.
Creative America, a studio- and union-supported group that fights piracy, launched a television advertising campaign that it said would air in the districts of key legislators. In Times Square, it turned on a digital pro-SOPA and PIPA billboard for the day - in space provided by News Corp, which owns Fox Studios.
The group also said it is sending a team of 20 organizers to big events around the country, including the upcoming Sundance Film Festival, to try to get voters to see the situation their way.
The legislation, known as PIPA in the Senate and SOPA in the House of Representatives, has been a priority for entertainment companies, publishers, pharmaceutical companies and other industry groups who say it is critical to curbing online piracy, which they believe costs them billions of dollars a year.
But Internet players argue the bills would undermine innovation and free speech rights and would compromise the functioning of the Internet.
In switching their positions, Blunt called the legislation "deeply flawed" while Rubio and Boozman cited "unintended consequences" that could stem from the proposed law. All said they still supported taking action against online piracy.
Other lawmakers, such as Senator Kristen Gillibrand, said they supported changes to the legislation.
The blackout affected thousands of sites and served as the culmination of several efforts online to fight the legislation. In recent days, for example, many Twittter users placed black "Stop SOPA" bands on the bottom of their profile pictures.
Even sites that didn't black out their sites, which would have cost them a day's worth of advertising revenue and angered some consumers, made their opposition to the bills plain.
"We can't let poorly thought out laws get in the way of the Internet's development," Facebook chief executive Mark Zuckerberg said in a statement.
Zynga issued a blog post complaining that "the overly broad provisions we've seen in the pending SOPA and PIPA bills could be used to target legitimate U.S. sites and chill innovation at a time when it is needed most."
While the Facebook and Zynga sites functioned as normal, others looked jarringly different.
Wikipedia mounted a 24-hour protest starting at midnight by converting their English page to a shadowy black background and warning readers that "the U.S. Congress is considering legislation that could fatally damage the free and open Internet."
It included a link to help Internet users contact their representatives.
Craigslist, the free Internet classifieds site, also went black in protest, while Google's home search page included a black bar slapped over its logo and asked readers: "Tell Congress: Please don't censor the web!"
Smaller sites, such as Reddit.com and BoingBoing.net, were also dark, while icanhascheezburger.com placed a banner over its site alerting users to the situation and inviting them to click on a link for more information.
"It's a way of engaging the public in something that had been a very much behind closed doors, kind of business as usual in Washington thing," said Bill Allison, editorial director at the Sunlight Foundation, a lobbying watchdog group. "It's a way to get the public aware and alerted to it, and somewhat on their side."
A lunchtime protest in San Francisco drew about 100 protesters, including Craigslist founder Craig Newmark and rapper M.C. Hammer, who called the proposed legislation "barbaric."
But content providers said the protests were long on hype and short on substance, and that reaching voters one-on-one and in person would prove more effective. "We see this as a long battle," said Mike Nugent, executive director of Creative America. He has been sending outreach staff to events like local festivals and movie screenings to get them to call their legislators and enlist their support.
MOMENTUM COOLS
The bills were seemingly on track for approval by Congress, but sentiment has shifted in recent weeks and an implicit veto threat from the White House over the weekend cast doubt on whether the legislation would pass.
Republican Representative Tom Price, head of the House Republican Policy Committee, said in a hallway interview, "I don't think it is going anywhere."
"There is real confusion about it, number one, but number two, there are real concerns about whether or not it would shut down the ability of entrepreneurs, new businesses and the like to utilize the Internet for their purposes," Price said.
When asked about the anti-piracy legislation at a news conference on Wednesday, House Speaker John Boehner said lawmakers will continue to try to find support for it, but that it's not there now.
"It's pretty clear to many of us that there is a lack of consensus at this point," Boehner said.
The protest drew some criticism ahead of its launch.
"This publicity stunt does a disservice to its users by promoting fear instead of facts," Lamar Smith, Republican chairman of the House Judiciary Committee and a sponsor of SOPA, said in a statement on Tuesday. "Perhaps during the blackout, Internet users can look elsewhere for an accurate definition of online piracy."
Former Senator Chris Dodd, who now chairs the Motion Picture Association of America, labeled the blackout a "gimmick" and called for its supporters to "stop the hyperbole and PR stunts and engage in meaningful efforts to combat piracy."
The blackout harkens back to some similar movements on the Internet in recent years, particularly a 2007 protest over online radio royalties. Then, services like Pandora turned off their music for a day. Two years later, the music services and record labels reached an agreement over the payments.
(Reporting by Sarah McBride in San Francisco and Diane Bartz in Washington D.C.; Additional reporting by Jasmin Melvin, Malathi Nayak, Alistair Barr and Thomas Ferraro; Editing by Maureen Bavdek, Tim Dobbyn, Gary Hill)
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